Cord Blood vs. Cord Tissue

What is the difference between Cord Blood and Cord Tissue?

The main difference between cord blood and cord tissue is the type of stem cells that are found in each of them.

Hematopoietic stem cells (HSCs) are found in the umbilical cord blood. These HSCs are the type of stem cells used to treat over 80 diseases currently. HSCs can develop into various blood forming cells to treat blood-related conditions and disorders including lymphoma and leukemia.

Mesenchymal stem cells (MSCs) are multipotent stromal cells found in the umbilical cord tissue that can be differentiated into many types of cells such as muscle (myocytes), bone (osteoblasts), cartilage (chondrocytes), and fat (adipocytes) cells. Research of MSCs is growing at a rapid pace globally.  Currently, MSCs is the subject of over 300 clinical trials with the potential to someday treat conditions such as heart disease, Alzheimer’s, arthritis, skin burns and injuries to bones and cartilage.

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Why bank both Cord Blood and Cord Tissue?

You may bank both cord blood and cord tissue once the baby is born as this can only be collected at birth.  Consider this as insurance for the future.  Cord blood is already proven to treat over 80 diseases with more trials still being conducted to discover more potential uses.  Cord tissue although still in clinical trials is looking very promising because it has the potential to treat a wide range of conditions and it can be regenerated providing the possibility for multiple treatments.

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Treatable Diseases

Over 80 types of diseases are proven treatable by Cord Blood Stem Cells Transplantation.

Acute Leukemias

  • Acute Biphenotypic Leukemia
  • Acute Lymphoblast Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Undifferentiated Leukemia

Chronic Leukemias

  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes

  • Amyloidosis
  • Chronic Myelomonocytic Leukemia (CMML)
  • Refractory Anemia (RA)
  • Refractory Anemia with Excess Blasts (RAEB)
  • Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
  • Refractory Anemia with Ringed Sideroblasts (RARS)

Stem Cell Disorders

  • Aplastic Anemia (Severe)
  • Congenital Cytopenia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)

Myeloproliferative Disorders

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (myelofibrosis)
  • Essential Thrombocythemia
  • Polycythemia Vera

Lymphoproliferative Disorders

  • Hodgkin’s Disease
  • Non-Hodgkin’s Lymphoma
  • Prolymphocytic Leukemia

Phagocyte Disorders

  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis

Liposomal Storage Diseases/ Inherited Metabolic Disorders

  • Adrenoleukodystrophy
  • Alpha Mannosidosis
  • Gaucher’s Disease
  • Hunter’s Syndrome (MPS-II)
  • Hurler’s Syndrome (MPS-IH)
  • Krabbe Disease
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Metachromatic Leukodystrophy
  • Morquio Syndrome (MPS-IV)
  • Mucolipidosis II (I-cell Disease)
  • Mucopolysaccharidoses (MPS)
  • Niemann-Pick Disease
  • Sanfilippo Syndrome (MPS-III)
  • Scheie Syndrome (MPS-IS)
  • Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
  • Wolman Disease

Histiocytic Disorders

  • Familial Erythrophagocytic Lymphohistiocytosis
  • Hemophagocytosis
  • Histiocytosis-X
  • Langerhans’ Cell Histiocytosis

Inherited Erythrocyte Abnormalities

  • Beta Thalassemia Major
  • Blackfan-Diamond Anemia
  • Pure Red Cell Aplasia
  • Sickle Cell Disease

Congenital (Inherited) Immune System Disorders

  • Absence of T & B Cells SCID
  • Absence of T Cells, Normal B Cell SCID
  • Ataxia-Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Kostmann Syndrome
  • Leukocyte Adhesion Deficiency
  • Omenn’s Syndrome
  • Severe Combined Immunodeficiency (SCID)
  • SCID with Adenosine Deaminase Deficiency
  • Wiskott-Aldrich Syndrome
  • X-Linked Lymphoproliferative Disorder

Inherited Platelet Abnormalities

  • Amegakaryocytosis / Congenital Thrombocytopenia

Other Inherited Disorders

  • Cartilage-Hair Hypoplasia
  • Ceroid Lipofuscinosis
  • Congenital Erythropoietic Porphyria
  • Glanzmann Thrombasthenia
  • Lesch-Nyhan Syndrome
  • Osteopetrosis
  • Sandhoff Disease
  • Tay Sachs Disease

Plasma Cell Disorders

  • Multiple Myeloma
  • Plasma Cell Leukemia
  • Waldenstrom’s Macroglobulinemia

Other Malignancies

  • Brain Tumors
  • Breast Cancer
  • Ewing Sarcoma
  • Neuroblastoma
  • Ovarian Cancer
  • Renal Cell Carcinoma
  • Retinoblastoma
  • Small-Cell Lung Cancer
  • Testicular Cancer

Autoimmune Diseases

  • Evan Syndrome

Emerging Stem Cell Applications

  • Alzheimer’s Disease
  • Cardiac Disease
  • Diabetes
  • Liver Disease
  • Lupus
  • Multiple Sclerosis
  • Muscular Dystrophy
  • Parkinson’s Disease
  • Rheumatoid Arthritis
  • Spinal Cord Injury
  • Stroke

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