Yield of total nucleated cells (TNC) is also called the recovery rate of TNC. The yield of total nucleated cells is the percentage of TNC that is extracted during processing. The higher the yield, the better.
Yield of TNC (%) = (Number of TNC extracted from processing/Total TNC before processing) x 100%
The yield of TNC is the most important processing quality indicator because it indicates how well a cord blood sample has been processed, regardless of the volume of the cord blood that was collected from the baby at birth.
Note: Total nucleated cells (TNC) are the most reliable indicator for a successful transplant (Moroff G et al. Transplantation and Cellular Engineering (2006) 46:507-515).